The Evoluent™ VerticalMouse™ 3 is the advanced third generation of the revolutionary mouse from the inventor of the handshake grip. Many users said earlier models relieved their wrist and arm pain.Approved ergonomic mouse of University of California at BerkeleyThe Evoluent VerticalMouse 2 was evaluated in 2007 by a team at the health services clinic in UC Berkeley, including medical doctors, physical therapists, ergonomists, and administrators. It was found to be comfortable, easily adapted to, and promote a neutral wrist and forearm posture. It is the only vertical type mouse approved for staff use within UC Berkeley and for sale in the campus store.